Review
doi: 10.1016/s0014-827x(01)01025-4.
Structure-based design of non-peptide HIV protease inhibitors
Affiliations
- PMID: 11347961
- DOI: 10.1016/s0014-827x(01)01025-4
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Review
Structure-based design of non-peptide HIV protease inhibitors
Farmaco.
2001 Jan-Feb.
Abstract
A number of structurally novel P2-ligands have been designed and synthesized. Incorporation of these ligands in the (R)-(hydroxyethyl)sulfonamide isostere provided a series of potent non-peptidyl HIV protease inhibitors.
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