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. 2001 Feb;15(1):63-7.

Endometrial patterns and endocrinologic characteristics of asymptomatic menopausal women

K Göl  1 , F Saraçoğlu, A Ekici, I Sahin
Affiliations
  • PMID: 11293927

Endometrial patterns and endocrinologic characteristics of asymptomatic menopausal women

K Göl et al. Gynecol Endocrinol. 2001 Feb.

Abstract

The endometrial histology and endocrinologic and demographic characteristics of 556 asymptomatic postmenopausal women, who attended the menopause outpatient clinic at Ankara Numune Education and Research Hospital were studied before initiating estrogen replacement therapy. Of these women, 486 (87.4%) had atrophic endometrium, 37 (6.65%) had proliferative endometrium, 27 (4.86%) had endometrial hyperplasia without atypia, three (0.54%) had endometrial hyperplasia with atypia and three (0.54%) had endometrial adenocarcinoma on their biopsy specimens. When demographic characteristics of the patients were considered, we found that the patients with endometrial adenocarcinoma and endometrial hyperplasia with atypia had potential risk factors for endometrial pathology such as chronic anovulation, diabetes or hypertension. This study confirms that routine endometrial sampling in asymptomatic postmenopausal women is not warranted, but patients with associated risk factors should be screened for endometrial pathology before starting estrogen replacement therapy.

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