Proteomics: a link between genomics, genetics and physiology
- PMID: 11198419
- DOI: 10.1023/a:1026525406953
Proteomics: a link between genomics, genetics and physiology
Abstract
Thanks to spectacular advances in the techniques for identifying proteins separated by two-dimensional electrophoresis and in methods for large-scale analysis of proteome variations, proteomics is becoming an essential methodology in various fields of plant biology. In the study of pleiotropic effects of mutants and in the analysis of responses to hormones and to environmental changes, the identification of involved metabolic pathways can be deduced from the function of affected proteins. In molecular quantitative genetics, proteomics can be used to map translated genes and loci controlling their expression, which can be used to identify proteins accounting for the variation of complex phenotypic traits. Linking gene expression to cell metabolism on the one hand and to genetic maps on the other, proteomics is a central tool for functional genomics.
Similar articles
-
[Advances in plant proteomics. II. Application of proteome techniques to plant biology research].Yi Chuan. 2006 Dec;28(12):1633-48. doi: 10.1360/yc-006-1633. Yi Chuan. 2006. PMID: 17138554 Review. Chinese.
-
Protein and Proteome Atlas for Plants under Stresses: New Highlights and Ways for Integrated Omics in Post-Genomics Era.Int J Mol Sci. 2019 Oct 21;20(20):5222. doi: 10.3390/ijms20205222. Int J Mol Sci. 2019. PMID: 31640274 Free PMC article. Review.
-
Seed dormancy and germination.Curr Opin Plant Biol. 2002 Feb;5(1):33-6. doi: 10.1016/s1369-5266(01)00219-9. Curr Opin Plant Biol. 2002. PMID: 11788305 Review.
-
Physiological and biotechnological implications of transcript-level variation under abiotic stress.Plant Biol (Stuttg). 2013 Nov;15(6):925-30. doi: 10.1111/plb.12075. Epub 2013 Aug 29. Plant Biol (Stuttg). 2013. PMID: 24033916 Review.
-
Combining proteomic and genetic studies in plants.J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Dec 25;782(1-2):137-49. doi: 10.1016/s1570-0232(02)00553-6. J Chromatogr B Analyt Technol Biomed Life Sci. 2002. PMID: 12458003 Review.
Cited by
-
Genetic contributions to intergroup responses: a cautionary perspective.Front Hum Neurosci. 2012 Aug 6;6:223. doi: 10.3389/fnhum.2012.00223. eCollection 2012. Front Hum Neurosci. 2012. PMID: 22888315 Free PMC article. No abstract available.
-
Proteomic survey of metabolic pathways in rice.Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11969-74. doi: 10.1073/pnas.172183199. Epub 2002 Aug 5. Proc Natl Acad Sci U S A. 2002. PMID: 12163647 Free PMC article.
-
Neuronal Circuit-Based Computer Modeling as a Phenotypic Strategy for CNS R&D.Front Neurosci. 2019 Jul 16;13:723. doi: 10.3389/fnins.2019.00723. eCollection 2019. Front Neurosci. 2019. PMID: 31379482 Free PMC article.
-
A new strategy for estimating recombination fractions between dominant markers from an F2 population.Genetics. 2007 Feb;175(2):923-31. doi: 10.1534/genetics.106.064030. Epub 2006 Oct 22. Genetics. 2007. PMID: 17057236 Free PMC article.
-
Mapping QTLs regulating morpho-physiological traits and yield: case studies, shortcomings and perspectives in drought-stressed maize.Ann Bot. 2002 Jun;89 Spec No(7):941-63. doi: 10.1093/aob/mcf134. Ann Bot. 2002. PMID: 12102519 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources