Review
doi: 10.1101/gr.157400.
Automation for genomics, part two: sequencers, microarrays, and future trends
Affiliations
- PMID: 10984447
- DOI: 10.1101/gr.157400
Item in Clipboard
Review
Automation for genomics, part two: sequencers, microarrays, and future trends
Genome Res.
2000 Sep.
Free article
Abstract
Automation for genomics has enabled a 43-fold increase in the total finished human genomic sequence in the world in the past four years. This is the second half of a two-part, noncomprehensive review that presents an overview of different types of automation equipment used in genome sequencing. The first part of the review, published in the previous issue, focused on automated procedures used to prepare DNA for sequencing or analysis. This second part of the review presents a look at available DNA sequencers and array technology and concludes with a look at future technologies. Alternate sequencing technologies including mass spectrometry, biochips, and single molecule analysis are included in this review.
Similar articles
-
Automation for genomics, part one: preparation for sequencing.Genome Res. 2000 Aug;10(8):1081-92. doi: 10.1101/gr.101400. Genome Res. 2000. PMID: 10958626 Review.
-
The death of microarrays?Nature. 2008 Oct 16;455(7215):847. doi: 10.1038/455847a. Nature. 2008. PMID: 18923476 No abstract available.
-
DNA microarrays: an introduction to the technology.Methods Mol Biol. 2009;509:1-14. doi: 10.1007/978-1-59745-372-1_1. Methods Mol Biol. 2009. PMID: 19212711 Review.
-
[A long-awaited revolution].Med Sci (Paris). 2008 Oct;24(10):869-73. doi: 10.1051/medsci/20082410869. Med Sci (Paris). 2008. PMID: 18950585 Review. French. No abstract available.
-
GenCompass: a universal system for analysing gene expression for any genome.Trends Biotechnol. 2004 Nov;22(11):552-5. doi: 10.1016/j.tibtech.2004.08.013. Trends Biotechnol. 2004. PMID: 15491796
Cited by
-
Evaluation of methods for sequence analysis of highly repetitive DNA templates.J Biomol Tech. 2006 Apr;17(2):138-44. J Biomol Tech. 2006. PMID: 16741241 Free PMC article.
-
Keeping up with the next generation: massively parallel sequencing in clinical diagnostics.J Mol Diagn. 2008 Nov;10(6):484-92. doi: 10.2353/jmoldx.2008.080027. Epub 2008 Oct 2. J Mol Diagn. 2008. PMID: 18832462 Free PMC article. Review.
-
Fluorescence spectral properties of labeled thiolated oligonucleotides bound to silver particles.Biopolymers. 2004 Jun 15;74(3):263-71. doi: 10.1002/bip.20071. Biopolymers. 2004. PMID: 15150802 Free PMC article.
-
MEGAN analysis of metagenomic data.Genome Res. 2007 Mar;17(3):377-86. doi: 10.1101/gr.5969107. Epub 2007 Jan 25. Genome Res. 2007. PMID: 17255551 Free PMC article.
-
MetaSim: a sequencing simulator for genomics and metagenomics.PLoS One. 2008 Oct 8;3(10):e3373. doi: 10.1371/journal.pone.0003373. PLoS One. 2008. PMID: 18841204 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
