doi: 10.1016/s0925-4773(00)00332-4.
Pax2, Otx2, Gbx2 and Fgf8 expression in early otic vesicle development
Affiliations
- PMID: 10906468
- DOI: 10.1016/s0925-4773(00)00332-4
Item in Clipboard
Pax2, Otx2, Gbx2 and Fgf8 expression in early otic vesicle development
Mech Dev.
2000 Jul.
Free article
Abstract
The inner ear is a suitable system to study the mechanisms involved in the specification of different functional domains during morphogenesis. Using single and double in situ hybridization (ISH) we show that three transcription factors (Otx2, Gbx2and Pax2) and a member of the fibroblast growth factor family (Fgf8) could participate in the compartmentalization of the otic vesicle and in the formation of the acoustic-vestibular ganglion.
Similar articles
-
Otx2, Gbx2, and Fgf8 expression patterns in the chick developing inner ear and their possible roles in otic specification and early innervation.Gene Expr Patterns. 2004 Oct;4(6):659-69. doi: 10.1016/j.modgep.2004.04.008. Gene Expr Patterns. 2004. PMID: 15465488
-
Differential expression of Otx2, Gbx2, Pax2, and Fgf8 in the developing vestibular and auditory sensory organs.Brain Res Bull. 2002 Feb-Mar 1;57(3-4):321-3. doi: 10.1016/s0361-9230(01)00725-0. Brain Res Bull. 2002. PMID: 11922981
-
Tissue-specific requirements for FGF8 during early inner ear development.Mech Dev. 2009 Oct;126(10):873-81. doi: 10.1016/j.mod.2009.07.004. Epub 2009 Jul 18. Mech Dev. 2009. PMID: 19619645
-
The development of the vertebrate inner ear.Mech Dev. 1998 Feb;71(1-2):5-21. doi: 10.1016/s0925-4773(97)00155-x. Mech Dev. 1998. PMID: 9507049 Review.
-
Induction of the inner ear: stepwise specification of otic fate from multipotent progenitors.Hear Res. 2013 Mar;297:3-12. doi: 10.1016/j.heares.2012.11.018. Epub 2012 Nov 27. Hear Res. 2013. PMID: 23194992 Review.
Cited by
-
Analysis of FGF-dependent and FGF-independent pathways in otic placode induction.PLoS One. 2013;8(1):e55011. doi: 10.1371/journal.pone.0055011. Epub 2013 Jan 23. PLoS One. 2013. PMID: 23355906 Free PMC article.
-
Pluripotent stem cell-derived cochlear cells: a challenge in constant progress.Cell Mol Life Sci. 2019 Feb;76(4):627-635. doi: 10.1007/s00018-018-2950-5. Epub 2018 Oct 19. Cell Mol Life Sci. 2019. PMID: 30341460 Free PMC article. Review.
-
CRABP-I Expression Patterns in the Developing Chick Inner Ear.Biology (Basel). 2023 Jan 10;12(1):104. doi: 10.3390/biology12010104. Biology (Basel). 2023. PMID: 36671796 Free PMC article.
-
Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons.Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17061-17070. doi: 10.1073/pnas.1902148116. Epub 2019 Aug 2. Proc Natl Acad Sci U S A. 2019. PMID: 31375626 Free PMC article.
-
A molecular analysis of neurogenic placode and cranial sensory ganglion development in the shark, Scyliorhinus canicula.Dev Biol. 2007 Apr 1;304(1):156-81. doi: 10.1016/j.ydbio.2006.12.029. Epub 2006 Dec 19. Dev Biol. 2007. PMID: 17234174 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
