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Review
. 1999 Jun 3;9(11):R400-2.
doi: 10.1016/s0960-9822(99)80253-x.

Oxidative stress: Protein folding with a novel redox switch

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Free article
Review

Oxidative stress: Protein folding with a novel redox switch

L W Ruddock et al. Curr Biol. .
Free article

Abstract

A novel cellular response to oxidative stress has been discovered, in which the activity of a molecular chaperone, Hsp33, is modulated by the environmental redox potential. This provides a rapid first defence mechanism against the potentially very harmful toxic effects of oxidative stress.

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