Oxidative stress: Protein folding with a novel redox switch
- PMID: 10359689
- DOI: 10.1016/s0960-9822(99)80253-x
Oxidative stress: Protein folding with a novel redox switch
Abstract
A novel cellular response to oxidative stress has been discovered, in which the activity of a molecular chaperone, Hsp33, is modulated by the environmental redox potential. This provides a rapid first defence mechanism against the potentially very harmful toxic effects of oxidative stress.
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