Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Jan;34(1):1-4.
doi: 10.1007/s11745-999-330-7.

Sex- and age-related differences in ceramide dihexosides of primary human brain tumors

A J Yates  1 , T K Franklin, B W Scheithauer, P C Burger, D K Pearl
Affiliations

Sex- and age-related differences in ceramide dihexosides of primary human brain tumors

A J Yates et al. Lipids. 1999 Jan.

Abstract

Neutral glycolipids (NGL) are promising diagnostic markers of human gliomas, but differences in NGL with age and sex have not been examined. Previous work demonstrated that ceramide dihexosides (CDH) levels in mouse kidney are age- and sex-dependent, probably due to levels of sex hormones. We quantitated CDH in 181 human gliomas and found significant differences with sex and age, particularly menopause and male puberty. This emphasizes the importance of assessing results of studies on glycolipids in disease states with respect to age and sex in order to avoid erroneous conclusions concerning the relationship of glycolipid composition with diagnosis and pathogenesis.

PubMed Disclaimer

Similar articles

See all similar articles

References

    1. J Biol Chem. 1994 Apr 15;269(15):11138-46 - PubMed
    1. Endocrinology. 1983 Jul;113(1):251-8 - PubMed
    1. J Lipid Res. 1970 Mar;11(2):158-63 - PubMed
    1. J Cell Physiol. 1986 Dec;129(3):390-4 - PubMed
    1. Clin Chim Acta. 1972 Apr;38(1):147-53 - PubMed

Publication types

LinkOut - more resources