Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity

Mark K Slifka; Rafi Ahmed

doi:10.1016/0966-842X(96)10059-7

. 1999 Mar 19;4(10):394–400. doi: 10.1016/0966-842X(96)10059-7

Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity

Mark K Slifka ¹, Rafi Ahmed ^1,^*

PMCID: PMC7133309 PMID: 8899965

Abstract

Despite extensive documentation of prolonged antibody responses following vaccination or acute viral infection, the mechanisms behind long-term antibody production are not fully understood. We propose the hypothesis that long-lived plasma cells are an important, yet largely overlooked, component of long-term humoral immunity.

References

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Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity

Mark K Slifka

Rafi Ahmed

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Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity

Mark K Slifka

Rafi Ahmed

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