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. 1973 Apr;70(4):1184–1185. doi: 10.1073/pnas.70.4.1184

Amino-Acid Acceptor Activity of the “70S-Associated” 4S RNA from Avian Myeloblastosis Virus

Leonard J Rosenthal 1,*, Paul C Zamecnik 1,
PMCID: PMC433453  PMID: 4352225

Abstract

The “70S-associated” 4S RNA from avian myeloblastosis virus contains transfer RNA, as determined by aminoacylation. The various amino acids esterified, plus the great number of minor bases found in this “70S-associated” 4S RNA indicate that a sizeable fraction, but not all, of this RNA is transfer RNA.

Keywords: oncogenic RNA virus, tRNA bound to 70S RNA

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Erikson E., Erikson R. L. Association of 4S ribonucleic acid with oncornavirus ribonucleic acids. J Virol. 1971 Aug;8(2):254–256. doi: 10.1128/jvi.8.2.254-256.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. McCain B., Biswal N., Benyesh-Melnick M. The subunits of murine sarcoma-leukaemia virus RNA. J Gen Virol. 1973 Jan;18(1):69–74. doi: 10.1099/0022-1317-18-1-69. [DOI] [PubMed] [Google Scholar]
  3. Randerath K., Rosenthal L. J., Zamecnik P. C. Base composition differences between avian myeloblastosis virus transfer RNA and transfer RNA isolated from host cells. Proc Natl Acad Sci U S A. 1971 Dec;68(12):3233–3237. doi: 10.1073/pnas.68.12.3233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Rosenthal L. J., Zamecnik P. C. Minor base composition of "70S-associated" 4S RNA from avian myeloblastosis virus. Proc Natl Acad Sci U S A. 1973 Mar;70(3):865–869. doi: 10.1073/pnas.70.3.865. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Stephenson M. L., Wirthlin L. S., Scott J. F., Zamecnik P. C. The 3'-terminal nucleosides of the high molecular weight RNA of avian myeloblastosis virus. Proc Natl Acad Sci U S A. 1972 May;69(5):1176–1180. doi: 10.1073/pnas.69.5.1176. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Trávnícek M. RNA with amino acid-acceptor activity isolated from an oncogenic virus. Biochim Biophys Acta. 1968 Oct 29;166(3):757–759. [PubMed] [Google Scholar]
  7. Trávnícek M. Some properties of amino acid-acceptor RNA isolated from avian tumour virus BAI strain A (avian myeloblastosis). Biochim Biophys Acta. 1969 Jun 17;182(2):427–439. [PubMed] [Google Scholar]

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