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. 1985 Jun;82(12):4085–4089. doi: 10.1073/pnas.82.12.4085

Activation of expression of latent Epstein-Barr herpesvirus after gene transfer with a small cloned subfragment of heterogeneous viral DNA.

J Countryman, G Miller
PMCID: PMC397939  PMID: 2987963

Abstract

We previously found that a form of Epstein-Barr virus with rearranged DNA induces replication of latent Epstein-Barr virus. We now have found that one of three fragments of this rearranged DNA, when cloned in recombinant plasmids and used to transfect cells, can activate expression of several polypeptides from a latent viral genome. The 33-kDa protein that is the product of the active fragment is likely to be responsible for disruption of latency.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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