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Nature Communications logoLink to Nature Communications
. 2024 Apr 3;15:2882. doi: 10.1038/s41467-024-47285-6

Retraction Note: Pericyte loss influences Alzheimer-like neurodegeneration in mice

Abhay P Sagare 1,#, Robert D Bell 2,#, Zhen Zhao 1,#, Qingyi Ma 1, Ethan A Winkler 2, Anita Ramanathan 1, Berislav V Zlokovic 1,
PMCID: PMC10991248  PMID: 38570509

Retraction to: Nature Communications 10.1038/ncomms3932, published online 13 December 2013

The authors have retracted this article after concerns were raised about some of the data reported. Similarities were identified between representative image panels in Fig. 7, which shows tissue staining with four different anti-tau antibodies:

  • Fig. 7e and 7f (hippocampus in control AppSW/0 Pdgfrb+/+ mice) images show similarities in negative staining for tau on tissue sections with two different tau antibodies.

  • Fig. 7e and 7f (hippocampus in pericyte-deficient AppSW/0 Pdgfrb+/− mice) images show similarities in positive staining for tau on tissue sections with two different tau antibodies.

  • Fig. 7a and 7e (hippocampus in control AppSW/0 Pdgfrb+/+ mice) images show similarities in negative staining for tau on tissue sections with two different tau antibodies.

Due to the age of the paper, the authors no longer have access to all original data for this publication, and so can no longer be confident in the reliability of the data reported in this article. All authors agree to this retraction.


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