Skip to main content

Advertisement

Log in

The Impact of New Drug Launches on Longevity: Evidence from Longitudinal, Disease-Level Data from 52 Countries, 1982–2001

  • Published:
International Journal of Health Care Finance and Economics Aims and scope Submit manuscript

Abstract

We perform an econometric analysis of the effect of new drug launches on longevity, using data from the IMS Health Drug Launches database and the WHO Mortality Database. Under conservative assumptions, our estimates imply that the average annual increase in life expectancy of the entire population resulting from new drug launches is about one week, and that the incremental cost effectiveness ratio (new drug expenditure per person per year divided by the increase in life-years per person per year attributable to new drug launches) is about $6750—far lower than most estimates of the value of a statistical life-year.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Canada)

Instant access to the full article PDF.

Similar content being viewed by others

Explore related subjects

Discover the latest articles, news and stories from top researchers in related subjects.

References

  • Agency for Healthcare Research and Quality (2002). “MEPS H38Codebook: 1999 Full Year Consolidated Data File Codebook.”November 27, http://www.meps.ahrq.gov/Pubdoc/HC038/H38CB.pdf

  • Arias, E. (2002). “United States Life Tables, 2000.”National Vital Statistics Reports 51(3). (Hyattsville, MD: National Center for Health Statistics).

  • Berndt, Ernst, Margaret K. Kyle, and Davina Ling (2003). “The Long Shadow of Patent Expiration: Do Rx to OTC Switches Provide an Afterlife?.”In Robert C. Feenstra and Matthew D. Shapiro (eds.), Scanner Data and Price Indexes, Chicago: University of Chicago Press.

    Google Scholar 

  • Bresnahan, T. and R. Gordon (1997). The Economics of New Goods. Chicago: University of Chicago Press.

    Google Scholar 

  • Cutler, D. and M. McClellan (2001). “Is Technological Change in Medicine Worth It?”Health Affairs 20(5), 11–29.

    Google Scholar 

  • Danzon, P., Y. R. Wang, and L. Wang (2003). “The Impact of Price Regulation on the Launch Delay of New Drugs—A Study of Twenty-Five Major Markets in the 1990s.” http://hc.wharton.upenn.edu/danzon/PDF Files/LaunchDelayPaper.pdf.

  • Folland, S., A. Goodman, and M. Stano (2001). The Economics of Health and Health Care, third edition. Upper Saddle River, NJ: Prentice Hall.

    Google Scholar 

  • Getzen, T (1997). Health Economics: Fundamentals and Flow of Funds. New York, NY: John Wiley and Sons.

    Google Scholar 

  • Global Forum for Health Research (2002). The 10/90 Report on Health Research 2001–2002. Geneva: Global Forum for Health Research. ISBN 2-940286-07-8. http://www.globalforumhealth.org/pages/index.asp

  • Grier, Holcombe et al. (2003). “Addition of Ifosfamide and Etoposide to Standard Chemotherapy for Ewing’’s Sarcoma and Primitive Neuroectodermal Tumor of Bone.”New England Journal of Medicine 348(8), 694–701.

    Google Scholar 

  • Henderson, J. (1999). Health Economics and Policy. Cincinnati, OH: South-Western Publishing Co.

    Google Scholar 

  • IMS Health, http://www.ims-global.com/.

  • Kyle, M. K. (2003). “Product Entry in Global Pharmaceutical Markets: A Cross-National Study.”Unpublished paper, Carnegie-Mellon University.

  • Lichtenberg, F. (1996). “Do (More and Better) Drugs Keep People Out of Hospitals?” American Economic Review 86, 384–388.

    Google Scholar 

  • Lichtenberg, F. (2001). “Are the Benefits of Newer Drugs Worth Their Cost? Evidence from the 1996 MEPS.”Health Affairs 20(5), 241–251.

    Google Scholar 

  • Liu, Jin-Tan, James K. Hammitt, and Jin-Long Liu (1997). “Estimated Hedonic Wage Function and the Value of Life in a Developing Country.”Economics Letters 57, 353–358.

    Google Scholar 

  • Murphy, K. M. and R. H. Topel (2003). “The Economic Value of Medical Research.”In Kevin M. Murphy and Robert H. Topel (eds.), Measuring the Gains from Medical Research: An Economic Approach. Chicago: University of Chicago Press.

    Google Scholar 

  • Nordhaus, W. (2003). “The Health of Nations: The Contribution of Improved Health to Living Standards.”In Kevin M. Murphy and Robert H. Topel (eds.), Measuring the Gains from Medical Research: An Economic Approach. Chicago: University of Chicago Press.

    Google Scholar 

  • OECD Health Database. http://www.credes.fr/english/ecosante/oecd.htm.

  • Romer, Paul (1990). “Endogenous Technical Change.”Journal of Political Economy 98, S71-S102.

    Google Scholar 

  • Santerre, R. and S. Neun (2000). Health Economics: Theories, Insights, and Industry Studies, revised edition. Orlando, FL: Dryden Press.

    Google Scholar 

  • Simon, N. B., M. L. Cropper, A. Alberini, and S. Arora (1999). “Valuing Mortality Reductions in India: A Study of Compensating-Wage Differentials.”World Bank Working Paper Series #2078, March.

  • Stenestrand, U. et al. (2001). “Early Statin Treatment Following Acute Myocardial Infarction and 1-year Survival,”Journal of the American Medical Association 285(4), 430–436.

    Google Scholar 

  • United Nations, World Population Prospects Population Database, http://esa.un.org/unpp/index.asp?panel = 2.

  • U.S. Pharmacist (2002). “Cancer News,”Vol. 27(11), posted November 15, http://www.uspharmacist.com/index. asp?show=article&page = 8_999.htm

  • World Health Organization, WHO Mortality Database, http://www3.who.int/whosis/whsa/ftp/download.htm.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Frank R. Lichtenberg.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lichtenberg, F.R. The Impact of New Drug Launches on Longevity: Evidence from Longitudinal, Disease-Level Data from 52 Countries, 1982–2001. Int J Health Care Finance Econ 5, 47–73 (2005). https://doi.org/10.1007/s10754-005-6601-7

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10754-005-6601-7

Navigation