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Pelargonium sidoides-Extrakt (EPs® 7630): Zulassung bestätigt Wirksamkeit und Verträglichkeit

Pelargonium sidoides-extract (EPs® 7630): registration confirms efficacy and safety

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Summary

For centuries the roots of Pelargonium sidoides DC have been used in South African ethno-medicine for the treatment of respiratory diseases. In Germany, a medicinal product containing a special extract of this substance is among the group of self-medication products most widely bought at chemist's shops. In December 2005, the Federal Institute for Drugs and Medical Devices (BfArM, Bonn) approved a new license for its use as a drug. The following review focuses on the current pharmacological, toxicological and clinical data covering the efficacy and innocuousness of this drug when administered for the treatment of acute bronchitis.

Zusammenfassung

Wurzelstücke aus Pelargonium sidoides DC werden in der südafrikanischen Ethnomedizin seit Jahrhunderten zur Behandlung von Atemwegserkrankungen angewendet. Ein Fertigarzneimittel mit einem speziellen Extrakt aus dieser Droge zählt gegenwärtig in Deutschland zu den Selbstmedikationspräparaten, die in der Apotheke am häufigsten abgegeben werden. Das Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM, Bonn) hat dem Präparat im Dezember 2005 eine Neuzulassung als Arzneimittel erteilt. Die nachfolgende Übersicht fokussiert sich auf die aktuellen pharmakologischen, toxikologischen und klinischen Daten zur Wirksamkeit und Unbedenklichkeit im neu zugelassenen Anwendungsgebiet akute Bronchitis.

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Authors and Affiliations

  1. Institut für Umweltmedizin und Krankenhaushygiene, Universitätsklinikum Freiburg, Freiburg, Germany

    Andreas Conrad

  2. Institut für Pharmazie, Pharmazeutische Biologie, Freie Universität Berlin, Berlin, Germany

    Herbert Kolodziej

  3. Berlin, Germany

    Volker Schulz

Authors
  1. Andreas Conrad
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  2. Herbert Kolodziej
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  3. Volker Schulz
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Correspondence to Volker Schulz.

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Conrad, A., Kolodziej, H. & Schulz, V. Pelargonium sidoides-Extrakt (EPs® 7630): Zulassung bestätigt Wirksamkeit und Verträglichkeit. Wien Med Wochenschr 157, 331–336 (2007). https://doi.org/10.1007/s10354-007-0434-6

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  • DOI: https://doi.org/10.1007/s10354-007-0434-6

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