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The cytogenetic efficiency of the antitumor agents bleomycin and peplomycin is enhanced by the heart drug verapamil (isoptin)

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Summary

The induction of 2-break chromosome aberrations (dicentrics and ring chromosomes) in human lymphocytes by the antitumor agents bleomycin and peplomycin is strongly enhanced when those agents are applied together with the heart drug verapamil (isoptin).

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References

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Author information

Authors and Affiliations

  1. Institut für Strahlenbiologie, Universität Münster, D-4400, Münster, Germany

    W. Scheid, B. Oppelmann & H. Traut

Authors
  1. W. Scheid
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  2. B. Oppelmann
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  3. H. Traut
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Additional information

We thank Heinrich Mack Nachf./Illertissen (Germany) for generously supplying both the bleomycin and the peplomycin and Dr P. Engel, Illertissen, for valuable informations.

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Scheid, W., Oppelmann, B. & Traut, H. The cytogenetic efficiency of the antitumor agents bleomycin and peplomycin is enhanced by the heart drug verapamil (isoptin). Experientia 40, 746–747 (1984). https://doi.org/10.1007/BF01949756

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  • DOI: https://doi.org/10.1007/BF01949756

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