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PET in clinical oncology

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Abstract

Positron Emission Tomography (PET) is an imaging technique that produces cross sectional images based on tissue biochemical and physiological processes. PET complements other anatomic imaging techniques such as x-ray CT and magnetic resonance imaging (MRI). Fundamental processes such as glucose metabolism, oxygen metabolism, and blood flow can be imaged and quantified with PET, in addition to many other processes of both clinical and investigative interest. PET is now emerging as a clinical tool in oncology and is useful in noninvasively grading tumors, in determining tumor activity and recurrence, and in monitoring the effects of a variety of therapeutic interventions with tumors. While most of the applications of PET in oncology to date have been in brain tumors, the technique is now being applied in tumor evaluations outside of the central nervous system.

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Authors and Affiliations

  1. Division of Nuclear Medicine and Biophysics, Department of Radiological Sciences, UCLA School of Medicine, 90024, Los Angeles, California, USA

    Randall A. Hawkins & Michael E. Phelps

  2. Laboratory of Nuclear Medicine UCLA School of Medicine, University of California, 900 Veteran Avenue, 90024, Los Angeles, California, USA

    Randall A. Hawkins & Michael E. Phelps

  3. Laboratory of Biomedical and Environmental Sciences, UCLA School of Medicine, University of California, 900 Veteran Avenue, 90024, Los Angeles, California, USA

    Randall A. Hawkins & Michael E. Phelps

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  1. Randall A. Hawkins
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  2. Michael E. Phelps
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Operated for the U.S. Department of Energy by the University of California under Contract #DE-AC03-76-SF00012.

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Hawkins, R.A., Phelps, M.E. PET in clinical oncology. Cancer Metast Rev 7, 119–142 (1988). https://doi.org/10.1007/BF00046482

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