Hi Heng,
I am trying minimap2 on DNA methylation data from whole-genome bisulfite sequence assay. The data processing needs to align reads to only forward or reverse strand of reference genome. Is there an easy way to do that? Thanks!

Minimap2 is pretty easy to install and the speed is amazing. I would like to incorporate it as part of a pipeline for DNA methylation data I am working on. If mapping to one strand is possible, Minimap2 could easily be part of the pipeline and hopefully shorten the runtime a lot.

Yupeng