Frida is currently not able to spawn an application on a specific Android user. All spawned application are launched with the default user.

1|ASUS_Z017D_1:/sdcard # pm list users
Users:
        UserInfo{0:Owner:13} running
        UserInfo{10:Work profile:30} running
ASUS_Z017D_1:/sdcard #

Same application on different user can have different data and can be managed in different ways, an option allowing the selection of the user used during the spawn process in android should resolve this problem.

Native "am start" command has an option to select the user to start the application.

inode