For this sample, we've already generated the server and client stubs from helloworld.proto and we'll be using a specific reference platform.
Install gRPC:
$ pip install grpcio
Or, to install it system wide:
$ sudo pip install grpcio
Download the example
$ # Clone the repository to get the example code:
$ git clone https://github.com/grpc/grpc
$ # Navigate to the "hello, world" Python example:
$ cd grpc/examples/python/helloworld
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Run the server
$ python2.7 greeter_server.py &
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Run the client
$ python2.7 greeter_client.py
You can find a more detailed tutorial in gRPC Basics: Python