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robjgiff authored Sep 25, 2024
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## Overview

HCV-GLUE is a sequence-oriented resource for comparative genomic analysis of hepatitis C virus (HCV), developed using the [GLUE](https://github.com/giffordlabcvr/gluetools) software framework. It includes a web interface that can be used to create an HCV-GLUE web-server.
HCV-GLUE is a sequence-oriented resource for comparative genomic analysis of hepatitis C virus (HCV), developed using the [GLUE](https://github.com/giffordlabcvr/gluetools) software framework. It includes a web interface that can be used to create an **[HCV-GLUE web-server](http://hcv-glue.cvr.gla.ac.uk/#/home)**.

Hepatitis C virus (HCV) is a bloodborne RNA virus that primarily targets the liver, causing both acute and chronic hepatitis. Classified under the *Hepacivirus* genus within the *Flaviviridae* family, HCV is mainly transmitted through contact with infected blood. If left untreated, infection can lead to serious liver complications, such as cirrhosis and liver cancer. Direct-acting antiviral medications have dramatically improved cure rates and hold the potential to eliminate the virus. However, achieving global elimination faces significant challenges

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