CallMolecularConsensusReads vs. CallOverlappingConsensusBases vs. CallDuplexConsensusReads #899
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Description
I just have a quick question about consensus calling. For some time, my lab has been using CallMolecularConsensusReads to generate consensus calls. However, I was reading on the fgbio site about the tools CallOverlappingConsensusBases and CallDuplexConsensusReads. You didn’t mention anything about the latter two tools in the best practices document (https://github.com/fulcrumgenomics/fgbio/blob/main/docs/best-practice-consensus-pipeline.md). Would you kindly clarify for what the latter tools do that CallMolecularConsensusReads does not? Should we add those tools to our pipeline?