Some people run two SC-55 hardware units in parallel to get over the polyphony limitations of the SC-55 which affectes a few games (source):

There's a lot more stuff that exceeds the polyphony limits of the SC-55 and SC-55mkII than many people realize. For the most part though, the partial/voice reserve and priority schemes do an adequate job of minimizing the limitations, and even more-so where the composer has been mindful of their proper use.

You'll also encounter sequences that play "correctly" on an SC-55, but will have glaringly noticeable dropped notes on the SC-55mkII, despite its greater polyphony. I'd looked into this some time back, and came to the conclusion that the voice priority scheme wasn't being honored correctly in the SC-55, with the SC-55mkII providing the proper (but less acoustically pleasing) behavior.

Various hardware options can be used to address the polyphony limitations though. Not to keep re-posting my lousy recent photo, but I'm currently running two SC-55s and CM-64s in a split-channel configuration (even/odd) with my "MIDI General" setup, effectively resulting in a 48-voice SC-55.

One good example is the Warcraft 2 soundtrack (source):

I have a CLEAR example where the polyphony (or rather the "Voice Reserve" distribution) of the SC-55 MKII (28) is not enough, on the MKI even more so.
It's from Warcraft 2! 😲
It was composed on the SC-88 and the polyphony of the SC-55 is not enough for some of the tracks.
It's the most played midi game track next to Doom and Duke3D on the SC-55... the irony.

The SC-55 has low polyphony (28) and it uses something called "Voice Reserve" to distribute and prioritize the available polyphony across the channels.
BUT the default values (each reset) are totally wrong and reserve nothing for the 11-16 channels, making them cut off the sounds on many midi files if tracks 1-10 take all 28 available sounds.
The only way to change the Voice Reserve for each channel is by sysex or front panel.

Roland completely removed the "Voice Reserve" function from SC-88 and on, because 64 polyphony was enough not to bother with the distribution of it across the channels.

Here is the Warcraft 2 example on a real SC-55mk2. The bell sound is repeatedly cut off in the first 10 seconds:

https://www.youtube.com/watch?v=0ndCckv-lww

As a beneficial side effect, we might even achieve somewhat lower per-CPU-core usage by distributing the workload across two plugin instances (8 MIDI channels per each instance).