Notalgia Paresthetica Dermatologist Report of Symptom Burden and Treatment: Results from a Physician Survey

Authors

  • Brian S. Kim Icahn School of Medicine at Mount Sinai, New York, NY, USA
  • Sonja Ständer University Hospital Münster, Münster, Germany
  • Kenji Kabashima Kyoto University Graduate School of Medicine, Kyoto, Japan
  • Jennifer A. Mohawk Cara Therapeutics, Stamford, CT, USA
  • Sherri So Cara Therapeutics, Stamford, CT, USA
  • Joana Goncalves Cara Therapeutics, Stamford, CT, USA
  • Nilam Shah Cara Therapeutics, Stamford, CT, USA
  • Catherine Munera Cara Therapeutics, Stamford, CT, USA
  • Joseph C. Punzalan AplusA Bell Falla, Newark, NJ, USA
  • Romelia Argudo AplusA Bell Falla, Newark, NJ, USA
  • Mark Lebwohl Icahn School of Medicine at Mount Sinai, New York, NY, USA

DOI:

https://doi.org/10.2340/actadv.v104.39941

Keywords:

Notalgia paresthetica, pruritus, neuropathic itch, sensory neuropathy, dermatologist, physician survey

Abstract

Notalgia paresthetica (NP) is a sensory neuropathy characterized by chronic pruritus, skin pain, and other pathologic sensations affecting the mid-to-upper back. NP may be under-recognized and under-diagnosed, with limited data available on its symptom presentation and treatment patterns. NP-DERM was an internet-based survey of dermatologists (n = 650) from 8 different countries on their perspectives on NP symptoms and current treatment practices. Dermatologists typically treated a median of 12 patients with NP per month. Dermatologists reported that itch (pruritus) was the most common symptom for their patients with NP, followed by hyperpigmentation and sensitive skin. The most burdensome NP symptom was pruritus, followed by burning or hot sensation, and painful or raw skin. The most prescribed treatments included non-medicated skin care, topical corticosteroids, oral antihistamines, medicated topicals, and gabapentin or pregabalin. Physicians reported low satisfaction with available treatments. The most common reason for physicians to discontinue patients’ therapy was lack of response. 

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Published

2024-09-11

How to Cite

Kim, B. S. ., Ständer, S. ., Kabashima, K. ., Mohawk, J. A. ., So, S. ., Goncalves, J. ., … Lebwohl, M. . (2024). Notalgia Paresthetica Dermatologist Report of Symptom Burden and Treatment: Results from a Physician Survey. Acta Dermato-Venereologica, 104, adv39941. https://doi.org/10.2340/actadv.v104.39941