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Recombinant Lloviu virus as a tool to study viral replication and host responses

Fig 4

Cellular tropism of rLLOVcomp.

(A) Infection of MDMs derived from 2 donors with the indicated MOIs of rEBOV-ZsG and rLLOV-ZsG-IRins-EBOVUTR+tr, labeled rLLOV-ZsG. Fluorescent images taken at 2 dpi. Infections of (B) iPSC-derived hepatocytes (iHeps) or (C) iPSC-derived lung alveolar type 2 cells (iAT2s) with rEBOV-ZsG or rLLOV-ZsG at an MOI of 1. Images were taken with 10x objective.

Fig 4

doi: https://doi.org/10.1371/journal.ppat.1010268.g004