Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies
Fig 5
Structural comparison of the Fab–G peptide complexes.
(A) Ribbon representation of the Fab CB002.5–G peptide (left) and Fab CB017.5–G peptide (right) complexes, generated by superimposing the structurally conserved cystine noose. Each complex is shown separately for clarity and colored as in Figs 3 and 4. (B) Ribbon representation of the G peptide, shown in the conformation adopted when bound to Fab CB002.5 (blue) or Fab CB017.5 (green). The figure was generated by superimposing the cystine nooses of the G peptides (Cys173–Cys186). The two disulfide bonds are shown as sticks, with sulfur atoms colored yellow.