Inhibitors of Pathogen Intercellular Signals as Selective Anti-Infective Compounds
Figure 6
The AA Analogs Inhibit HAQ Production in B. thailandensis Cell Supernatants
Mass spectrometry (MS) determination of unsaturated HAQs in OD600 = 3 culture supernatants of B. thailandensis cells grown in the absence or presence of 3 mM 6FABA, 6CABA, or 4CABA. Note that while saturated HAQs, including HHQ, occur in B. thailandensis cells, their levels were below the quantification threshold.