LL-37 alone and in combination with IL17A enhances proinflammatory cytokine expression in parallel with hyaluronan metabolism in human synovial sarcoma cell line SW982—A step toward understanding the development of inflammatory arthritis
Fig 2
LL-37 induced HA metabolism in SW982 cell line.
SW982 cells were treated with 12.5 ng/mL of LL-37 for varied times. Cells were then collected and measured for the expression of HAS2, HAS3, HYAL1, HYAL2 and CD44 genes, respectively (A-E). The values from triplicate experiments are expressed as the mean ± SD of fold increases compared to the untreated control. Horizontal brackets indicate significance levels at *p < 0.05 or **p < 0.01.