Whole Transcriptome Profiling Identifies CD93 and Other Plasma Cell Survival Factor Genes Associated with Measles-Specific Antibody Response after Vaccination
Fig 1
Network biology of gene expression in measles vaccine high and low antibody responders.Simultaneous visualization of overall stimulation response (gene expression in response to viral stimulation in all subjects) and differential responses (in high vs. low antibody responders) within the context of a high-confidence biologic network. Each gene is represented as two circles, the outer colored by the virus-induced fold change in all subjects (FC, presented as log2 Stim FC) and the inner by the statistical interaction between high and low responders (i.e., difference in stimulated FC between the high and low antibody responder groups, presented as log2 FC between high and low responders).