Human Astrocytes: Secretome Profiles of Cytokines and Chemokines
Figure 4
Molecular network showing cytokine and chemokine secretomes of human astrocytes.
Entrez Gene IDs corresponding to 14 upregulated and 2 downregulated cytokines in IL-1β/TNF-α-activated human astrocytes were imported into the Ingenuity Pathways Analysis (IPA). The most significant molecular network relevant to the imported genes (red arrows) is shown. NF-kB is highlighted by blue circle. CCL5 (RANTES), CCL3 (MIP-1α), CXCL1 (GROα), CSF2 (GM-CSF), CSF3 (G-CSF), IL1R and IL1RAP are indicated by red.