Whole Transcriptome Sequencing Reveals Gene Expression and Splicing Differences in Brain Regions Affected by Alzheimer's Disease
Figure 2
Venn diagram showing distributions of differentially expressed transcripts between healthy and AD brain.
Venn diagram showing the number of differentially expressed transcripts between AD and normal tissue samples across total brain, temporal and frontal lobe. The number of transcripts unique to AD and normal tissues is shown in universe area outside the circles. The numbers of transcripts up-regulated by more than two-fold in AD tissue are indicated in the dark grey circle, while the numbers up-regulated by more than two-fold in normal tissue are highlighted in the light grey circle. The intersection of the two circles refers to number of transcripts which are expressed in both AD and normal tissues but which are less than two-fold different in expression level.