Cpd-1 Null Mice Display a Subtle Neurological Phenotype
Figure 4
Expression levels of LANP and APRIL do not alter in CPD1 null mice.
A. Brain lysates from CPD1 +/+, CPD1 +/−, and CPD1 −/− mice were subjected to western blot analysis with an anti-LANP antibody to check for protein levels of LANP. Lysate from LANP null mice served as control with actin as loading control. B. Brain lysates from CPD1 +/+, CPD1 +/−, and CPD1 −/− mice were subjected to western blot analysis to check for protein levels of APRIL with an APRIL antibody. C. mRNA expression analysis of CPD-1, LANP and APRIL was performed using quantitative PCR. GAPDH served as an internal control and the fold difference is relative to expression in wild type mice.