A High-Density Admixture Scan in 1,670 African Americans with Hypertension
Figure 2
An Analysis of LOD Scores at Varying Risk Models Reveals Weak Evidence for Association of Previously Published Loci with HTN
Using the distribution of LOD score shown below, we estimated a HTN odds ratio of 1.19 (95% credible interval 1.06–1.34) for inheritance of the African allele at the 6p24.1 (GATA184A08) locus, and odds ratios of 1.06 (0.94–1.21), 1.04 (0.95–1.17), and 1.02 (0.92–1.15) for the 2p25.1 (d2s1400), 21q21.1 (d21s1432), and 3q13.31 (d3s2460) loci, respectively.