Distributions of Transposable Elements Reveal Hazardous Zones in Mammalian Introns
Figure 5
Comparisons of TE frequency within the U-zone.
Three TE classes were examined and results were plotted in panel A, B, and C for the human Alu, human L1, and mouse LTR elements, respectively. In each plot, three groups of comparisons are shown: ‘U-zone’ stands for TE insertions within the U-zone; ‘antisense’ for human Alu or ‘sense’ for human L1 and mouse LTR indicates TEs within the U-zone in the corresponding orientation with respect to the enclosing gene; ‘<20 bp to SA’ indicates TE insertions within 20 bp of SA sites with an exception for human Alu and L1 mutagenic TEs (marked by shading), for which all cases were included due to limited total numbers. The y-axis shows the percentage of TEs that belong to the corresponding groups. Bars in each group represent mutagenic TE insertions (green), polymorphic TE insertions (light blue), all full-length TE insertions in the reference genome (yellow), and computational simulation as a random control (dark blue). Error bars represent standard errors derived from the total number of cases (sample size) for each category.