Hs.518270 | Chromosome 3 | Solute carrier family 21 (prostaglandin transporter), member 2 [SLCO2A1] | Transports PGD2, PGE1, PGF2 and PGF2A. May mediate release and transepithelial transport of newly synthesized prostaglandins. | 17.2 |
Hs.436893 | Chromosome 13 | Solute carrier family 15 (oligopeptide transporter), member 1 [SLC15A1] | Proton-coupled intake of oligopeptides (2-4 amino acids), with dipeptide preference. | 9.1 |
Hs.120759 | Chromosome 2 | Apolipoprotein B (including Ag [x] antigen) [APOB] | Recognition signal for cellular binding and internalization of LDL particles by apoB/E receptor. | 5.0 |
Hs.1290 | Chromosome 5 | Complement component C9 [C9] | Final component added in MAC formation. Responsible for formation of transmembrane channels. | 5.0 |
Hs.80485 | Chromosome 3 | Adipose most abundant gene transcript 1 [ACDC] | Negative regulator in haematopoesis. Inhibits endothelial NFκB signalling via cAMP dependent pathway. Inhibits TNFα expression of endothelial adhesion molecules. | 4.2 |
Hs.1408 | Chromosome 20 | Endothelin 1 [EDN3] | Endothelium derived vasoconstrictor. | 4.0 |
Hs.415768 | Chromosome 17 | Nerve growth factor receptor (TNFR superfamily, member 16). [NGFR] | Low-affinity receptor for NGF, BDNF, NT-3/NT-4 and mediates survival and cell death of neural cells. | 3.9 |
Hs.524368 | Chromosome 12 | Vitamin D (1, 25-dihydroxyvitamin D3) receptor. [VDR] | Nuclear hormone receptor. Mediator of vitamin D3 action. | 3.8 |
Hs.317632 | Chromosome 5 | Cadherin 18, type 2 [CDH1] | Calcium dependent cell adhesion protein. | 3.7 |
Hs.591484 | Chromosome 1 | Laminin gamma 2 [LAMC2] | Mediator of attachment, migration and organization of cells to tissues in embryogenesis by extracellular matrix interactions. Ladsin exerts cells scattering activity. | 3.5 |
Hs.632402 | Chromosome 1 | Connexin 59 gene [CX59/GJA10] or gap junction protein, alpha 10, 59kDa | Involved in the action of connexons, through which low-MW materials diffuse through cells. | 3.5 |
Hs.82890 | Chromosome 14 | Defender against cell death 1 [DAD1] | DAD1 loss triggers apoptosis. | 3.4 |
Hs.138378 | Chromosome 11 | Caspase 4-apoptosis related cysteine protease [CASP4] | Role in activation cascade of caspases, responsible for the execution of apoptosis. | 3.2 |
Hs.5302 | Chromosome 19 | Lectin, galactoside binding soluble (galectin 4) [LGALS4] | Binds lactose and related sugars. May be involved in the assembly of adherens junctions. | 3.1 |
Hs.35354 | Chromosome 3 | IGF-II mRNA binding protein 2 [IMP-2] | Nuclear mRNA splicing. | 3.0 |
Hs.2258 | Chromosome 11 | Matrix metalloproteinase 10 (stromelysin 2) [MMP10] | Degrades fibronectin, type I, III, IV and V gelatins and collagen III, IV and V. Activates procollagenase. | 3.0 |
Hs.25155 | Chromosome 10 | Neuroepithelial cell transforming gene 1 [NET1] | Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May activate SAPK/JNK pathway. | 2.9 |
Hs.421724 | Chromosome 14 | Cathepsin G [CTSG] | Proteolysis and peptidolysis. | 2.9 |
Hs.443031 | Chromosome 3 | Lysosomal beta galactosidase [GLB1] | Essential for activity of β galactosidase and neuraminidase. Can deamidate tachykinins. | 2.8 |