Abstract
Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.
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Acknowledgements
We thank B. Fell, C. Blackstone and C. Smith for valuable discussions. We regret that we could not cite all the relevant literature owing to space constraints.
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Youle, R., Karbowski, M. Mitochondrial fission in apoptosis. Nat Rev Mol Cell Biol 6, 657–663 (2005). https://doi.org/10.1038/nrm1697
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DOI: https://doi.org/10.1038/nrm1697
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