This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Goate, A. et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704–706 (1991).
Van Broeckhoven, C. Molecular genetics of Alzheimer disease: identification of genes and gene mutations. Eur. Neurol. 35, 8–19 (1995).
Sherrington, R. et al. Cloning of a gene bearing mis-sense mutations in early-onset familial Alzheimer's disease. Nature 375, 754–760 (1995).
Alzheimer's Disease Collaborative Group. The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nature Genet. 11, 219–222 (1995).
Cruts, M. et al. Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3. Hum. molec. Genet. (in the press).
Campion, D. et al. Mutations of the Presenilin-1 gene in families with early-onset Alzheimer's disease. Hum. molec. Genet. (in the press).
Tanahashi, H. et al. Missense mutation of S182 gene in Japanese familial Alzheimer's disease. The Lancet 346, 440 (1995).
Levy-Lahad, E. et al. A familial Alzheimer's disease locus on chromosome 1. Science 269, 970–973 (1995).
Levy-Lahad, E. et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269, 973–977 (1995).
Rogaev, E.I. et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775–778 (1995).
Levitan, D. & Greenwald, I. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377, 351–354 (1995).
Artavanis-Tsakonas, S., Matsuno, K. & Fortini, M.E. Notch signaling. Science 268, 225–232 (1995).
Scheuner, D. et al. Fibroblasts from carriers of familial AD linked to chromosome 14 show increased Aβ production. Soc. Neurosci. Abstr. 21, 1500 (1995).
Sorbi, S. et al. Missense mutation of S182 gene in Italian families with early-onset Alzheimer's disease. Lancet 346, 439–440 (1995).
Wasco, W. et al. Familial Alzheimer's chromosome 14 mutations. Nature Med. 1, 848 (1995).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Broeckhoven, C. Presenilins and Alzheimer disease. Nat Genet 11, 230–232 (1995). https://doi.org/10.1038/ng1195-230
Issue Date:
DOI: https://doi.org/10.1038/ng1195-230
