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Stem cells, asymmetric division and cancer

Nature Genetics volume 37, pages 1027–1028 (2005)Cite this article

Asymmetric division of stem cells results into two unequal daughter cells, only one of which resembles the parent stem cell. A new study provides genetic evidence in Drosophila melanogaster that the disturbance of this delicately balanced process in neuronal stem cells induces a cancer-like state.

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Figure 1: Asymmetric cell division in the neuroblast stem cell system of the D. melanogaster brain5.

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  1. the Hubrecht Laboratory and Centre for Biomedical Genetics, Uppsalalaan 8, 3584 CT, Utrecht, NL-3584, The Netherlands

    Hans Clevers

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  1. Hans Clevers
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Clevers, H. Stem cells, asymmetric division and cancer. Nat Genet 37, 1027–1028 (2005). https://doi.org/10.1038/ng1005-1027

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