Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Bi-directional Initiation of DNA Synthesis in Developing Chick Erythroblasts

Abstract

Measurement of the molecular weight of newly synthesized DNA in cultures containing BrUdR shows that initiation must proceed in two directions simultaneously from a site in the middle of the replicon.

This is a preview of subscription content, access via your institution

Access options

Similar content being viewed by others

References

  1. Huberman, J., and Riggs, A. D., J. Mol. Biol., 32, 327 (1968).

    Article  CAS  Google Scholar 

  2. Shnös, M., and Inman, R. B., J. Mol. Biol., 51, 61 (1970).

    Article  Google Scholar 

  3. Masters, M., and Broda, P., Nature, 232, 137 (1971).

    CAS  Google Scholar 

  4. Lark, K. G., Consigli, R., and Toliver, A., J. Mol. Biol., 58, 873 (1971).

    Article  CAS  Google Scholar 

  5. Weintraub, H., Campbell, G., and Holtzer, H., J. Cell Biol., 50, 652 (1971).

    Article  CAS  Google Scholar 

  6. Campbell, G., Weintraub, H., and Holtzer, H., J. Cell Biol., 50, 669 (1971).

    Article  CAS  Google Scholar 

  7. Wilt, F. H., J. Mol. Biol., 12, 331 (1965).

    Article  CAS  Google Scholar 

  8. Weintraub, H., and Holtzer, H., J. Mol. Biol. (in the press).

  9. Cleaver, J. E., Rad. Res., 37, 334 (1969).

    Article  CAS  Google Scholar 

  10. Tobia, A. M., Schildkraut, C. L., and Maio, J., J. Mol. Biol., 54, 499 (1970).

    Article  CAS  Google Scholar 

  11. Regan, J. D., Setlow, R. B., and Ley, R. D., Proc. US Nat. Acad. Sci., 68, 708 (1971).

    Article  CAS  Google Scholar 

  12. Hotz, G., and Walser, R., Photochem. Photobiol., 12, 207 (1970).

    Article  CAS  Google Scholar 

  13. Yoshikawa, H., and Haas, M., Cold Spring Harbor Symp. Quant. Biol., 33, 843 (1968).

    Article  CAS  Google Scholar 

  14. Maaløe, O., and Hanawalt, P. C., J. Mol. Biol., 3, 144 (1961).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

WEINTRAUB, H. Bi-directional Initiation of DNA Synthesis in Developing Chick Erythroblasts. Nature New Biology 236, 195–197 (1972). https://doi.org/10.1038/newbio236195a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/newbio236195a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing