Statins reduce the expression of the class II major histocompatibility complex (MHCII) by arterial cells, leading to a decreased T-cell response. This indicates that statins may be useful in treating graft atherosclerosis and other chronic inflammatory conditions. (pages 1399–1402)
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Palinski, W. Immunomodulation: a new role for statins?. Nat Med 6, 1311–1312 (2000). https://doi.org/10.1038/82107
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DOI: https://doi.org/10.1038/82107
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