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VEGF gene therapy: stimulating angiogenesis or angioma-genesis?

Nature Medicine volume 6, pages 1102–1103 (2000)Cite this article

The finding that unregulated, continuous delivery of vascular endothelial growth factor to the myocardium causes the formation of hemangiomas and death in mice indicates that more research is required on this potent molecule before clinical trials can proceed.

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  1. Center for Transgene Technology & Gene Therapy KU Leuven, Campus Gasthuisberg, Herestraat, 49 B-3000, Leuven, Belgium

    Peter Carmeliet

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  1. Peter Carmeliet
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Carmeliet, P. VEGF gene therapy: stimulating angiogenesis or angioma-genesis?. Nat Med 6, 1102–1103 (2000). https://doi.org/10.1038/80430

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