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Neuroscience

Alzheimer's disease

Nature volume 461, pages 895–897 (2009)Cite this article

The neurodegenerative disorder Alzheimer's disease is becoming more prevalent in ageing populations worldwide. The identification of effective treatments will require a better understanding of the physiological mechanisms involved, and innovative approaches to drug development and evaluation.

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Figure 1: Some key players in the pathogenesis of AD.
Figure 2: The challenge of finding AD biomarkers.

FURTHER READING

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Authors and Affiliations

  1. Lennart Mucke is at the Gladstone Institute of Neurological Disease and the Department of Neurology, University of California, San Francisco, California 94158, USA. lmucke@gladstone.ucsf.edu,

    Lennart Mucke

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  1. Lennart Mucke
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Competing interests

The author consults for Merck, has received research funding from Elan, and serves on the scientific advisory board of iPierian.

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See online at http://go.nature.com/phyLwm for more on neuroscience.

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Mucke, L. Alzheimer's disease. Nature 461, 895–897 (2009). https://doi.org/10.1038/461895a

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