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An encore for ribosome biogenesis in the control of cell proliferation

Nature Cell Biology volume 2, pages E71–E72 (2000)Cite this article

Abstract

Although the importance of cell growth for cell-cycle progression has been recognized for thirty years, the molecular basis of this relationship is poorly understood. However, researchers have begun to tease apart these two processes in model systems. This commentary focuses on one potential mechanism by which ribosome biogenesis antagonizes cell-cycle progression until the cell has grown to an adequate size.

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Figure 1: Control of cell proliferation through ribosome biogenesis.

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  1. the Friedrich Miescher Institute,, Maulbeerstrasse 66, Basel, CH-4058, Switzerland

    George Thomas

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  1. George Thomas
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Correspondence to George Thomas.

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Thomas, G. An encore for ribosome biogenesis in the control of cell proliferation. Nat Cell Biol 2, E71–E72 (2000). https://doi.org/10.1038/35010581

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