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Identification by anti-idiotype antibodies of an intracellular membrane protein that recognizes a mammalian endoplasmic reticulum retention signal

Nature volume 345, pages 495–502 (1990)Cite this article

A Retraction to this article was published on 26 November 1992

Abstract

Monoclonal antibodies were raised against antibodies to distinct carboxy-terminal KDEL sequences of two soluble, resident endoplasmic reticulum proteins. These anti-idiotype reagents recognize an intrinsic membrane protein with characteristics expected of a receptor responsible for the recognition and return of resident proteins to the endoplasmic reticulum.

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Author notes

  1. John Tooze and Stephen Fuller: To whom correspondence should be addressed.

Authors and Affiliations

  1. Cell Biology, European Molecular Biology Laboratory, Meyerhofstrasse l, 6900, Heidelberg, FRG

    David Vaux

  2. Biological Structures Programmes, European Molecular Biology Laboratory, Meyerhofstrasse l, 6900, Heidelberg, FRG

    John Tooze & Stephen Fuller

Authors
  1. David Vaux
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  2. John Tooze
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  3. Stephen Fuller
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Vaux, D., Tooze, J. & Fuller, S. Identification by anti-idiotype antibodies of an intracellular membrane protein that recognizes a mammalian endoplasmic reticulum retention signal. Nature 345, 495–502 (1990). https://doi.org/10.1038/345495a0

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