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Roles of G protein subunits in transmembrane signalling

Nature volume 333, pages 129–134 (1988)Cite this article

Abstract

A family of proteins called G proteins couples cell surface receptors to a variety of enzymes and ion channels. Since many cells contain several very similar G proteins, an important question is how signals remain specific as they cross the cell membrane.

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Authors and Affiliations

  1. Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital Harvard Medical School, Boston, Massachusetts, 02115, USA

    Eva J. Neer & David E. Clapham

  2. Departments of Pharmacology, Physiology and Biophysics, Mayo Foundation, Rochester, Minnesota, 55905, USA

    David E. Clapham

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  1. Eva J. Neer
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Neer, E., Clapham, D. Roles of G protein subunits in transmembrane signalling. Nature 333, 129–134 (1988). https://doi.org/10.1038/333129a0

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