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The structure of eight distinct cloned human leukocyte interferon cDNAs

Nature volume 290, pages 20–26 (1981)Cite this article

Abstract

Eight classes of human leukocyte interferon (LeIFN) cDNA clones have been identified in a cDNA library prepared from a myeloblastoid cell line. The nucleotide sequences demonstrate that the multiple human LeIFN genes code for a family of homologous, yet distinct proteins. One of the cDNA clones may have been derived from the transcription of a LeIFN pseudogene.

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Authors and Affiliations

  1. Department of Molecular Biology, Genentech, Inc., 460 Point San Bruno Boulevard, South San Francisco, California, 94080, USA

    David V. Goeddel, David W. Leung, Thomas J. Dull, Mitchell Gross, Richard M. Lawn, Peter H. Seeburg, Axel Ullrich, Elizabeth Yelverton & Patrick W. Gray

  2. Roche Institute of Molecular Biology, Nutley, New Jersey, 07110, USA

    Russell McCandliss

Authors
  1. David V. Goeddel
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  2. David W. Leung
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  4. Mitchell Gross
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  5. Richard M. Lawn
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  6. Russell McCandliss
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  7. Peter H. Seeburg
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  8. Axel Ullrich
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  9. Elizabeth Yelverton
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  10. Patrick W. Gray
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Goeddel, D., Leung, D., Dull, T. et al. The structure of eight distinct cloned human leukocyte interferon cDNAs. Nature 290, 20–26 (1981). https://doi.org/10.1038/290020a0

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