Abstract
We report the case of a 7 year old boy with fragile-X syndrome and epilepsy. In this patient, the detection of rolandic epileptiform potentials during sleep and hand tapping-evoked rolandic EEG spikes, together with giant somatosensory evoked potentials, further support the already suggested neurophysiological similarities between fragile-X syndrome and benign childhood epilepsy with centrotemporal spikes.
Sommario
Descriviamo il caso di un bambino di 7 anni affetto da sindrome del cromosoma X fragile ed epilessia. L'osservazione di potenziali epilettiformi rolandici durante il sonno, di punte rolandiche evocate dalla percussione della mano destra e di potenziali evocati somatosensoriali giganti, in questo paziente, fornisce unulteriore supporto alle somiglianze neurofisiologiche, già ipotizzate, tra sindrome del cromosoma X fragile ed epilessia a punte centrotemporali.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Dalla Bernardina B., Chiamenti C., Capovilla G., Colamaria V.:Benign partial epilepsies in childhood. In: Roger J., Dravet C., Bureau M., Dreifuss F. E., Wolf P. (eds.), Epileptic syndromes in infancy, childhood and adolescence. John Libbey, London, 137–149, 1985.
De Marco P., Tassinari C. A.:Extreme somatosensory evoked potential (ESEP): an EEG sign forecasting the possible occurrence of seizures in children. Epilepsia, 22: 569–575, 1981.
Musumeci S. A., Ferri R., Elia M., Colognola R. M., Bergonzi P., Tassinari C. A. Epilepsy and the fragile X syndrome: a follow-up study. Am. J. Med. Genet., 38: 511–513, 1991.
Plasmati R., Michelucci R., Forti A., Rubboli G., Salvi F., Saba E., Tassinari C. A.:The neurophysiological features of benign partial epilepsy with rolandic spikes. Epilepsy Res. Suppl. 6: 45–48, 1992.
Tassinari C. A., De Marco P., Plasmati R., Pantieri R., Blanco M., Michelucci R.:Extreme somatosensory evoked potentials (ESEPs) elicited by tapping of hands or feet in children: a somatosensory cerebral evoked potentials study. Neurophysiol. Clin., 18: 123–128, 1988.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Musumeci, S.A., Elia, M., Ferri, R. et al. Evoked spikes and giant somatosensory evoked potentials in a patient with fragile-X syndrome. Ital J Neuro Sci 15, 365–368 (1994). https://doi.org/10.1007/BF02339934
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02339934