Summary
Coronavirus-like particles were detected by electron microscopy in the intestinal contents of pigs during a diarrheal outbreak on 4 swine breeding farms. Diarrhea was reproduced in experimental pigs with one of the isolates, designated CV777, which was found to be distinct from the 2 known porcine coronaviruses, transmissible gastroenteritis virus and hemagglutinating encephalomyelitis virus.
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These studies were supported by the Institute for the Encouragement of Research in Industry and Agriculture (IWONL), Brussels, Belgium.
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Pensaert, M.B., de Bouck, P. A new coronavirus-like particle associated with diarrhea in swine. Archives of Virology 58, 243–247 (1978). https://doi.org/10.1007/BF01317606
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DOI: https://doi.org/10.1007/BF01317606