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The MYST Family of Histone Acetyltransferases

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Protein Complexes that Modify Chromatin

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 274))

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Abstract

Multiple chromatin modifying proteins and multisubunit complexes have been characterized in recent Years. Histone acetyltransferase (HAT) activities have been the most thoroughly studied, both biochemically and functionally. This review sums up the current knowledge on a specific group of proteins that is extremely well conserved throughout evolution, the MYST family of histone acetyltransferases. These proteins play critical roles in various nuclear functions and the control of cell proliferation.

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  1. Laval University Cancer Research Center, Hôtel-Dieu de Quebec (CHUQ), 11 Côte du Palais, Quebec City, QC, GIR 2J6, Canada

    R. T. Utley & J. Côté

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  1. Howard Hughes Medical Institute Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 306 Althouse Lab, University Park, PA, 16802, USA

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Utley, R.T., Côté, J. (2003). The MYST Family of Histone Acetyltransferases. In: Workman, J.L. (eds) Protein Complexes that Modify Chromatin. Current Topics in Microbiology and Immunology, vol 274. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55747-7_8

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