Abstract
During the past decade our laboratories have been studying the structure and functions of coronavirus glycoproteins. Several years ago, based on our studies with mouse hepatitis virus (MHV)-A59, we proposed a schematic model of the molecular organization of the coronavirus particle (Sturman et al., 1980). This model appears to be valid for most other coronaviruses as well (Garwes, 1980; Siddell et al., 1982). Our current representation of the structure of MHV-A59 is shown in Fig. 1 (Sturman and Holmes, 1983).
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Keywords
- Cell Fusion
- Infectious Bronchitis Virus
- Mouse Hepatitis Virus
- 180K Form
- Avian Infectious Bronchitis Virus
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© 1984 Plenum Press, New York
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Sturman, L.S., Holmes, K.V. (1984). Proteolytic Cleavage of Peplomeric Glycoprotein E2 of MHV Yields Two 90K Subunits and Activates Cell Fusion. In: Rottier, P.J.M., van der Zeijst, B.A.M., Spaan, W.J.M., Horzinek, M.C. (eds) Molecular Biology and Pathogenesis of Coronaviruses. Advances in Experimental Medicine and Biology, vol 173. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9373-7_3
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DOI: https://doi.org/10.1007/978-1-4615-9373-7_3
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