Collections open to submissions
Barrier immunology
Guest Editor
Hernán Peñaloza, PhD, Pontifical Catholic University of Chile, Chile
Submission Status: Open until 23 May 2025
Macrophage polarization
Guest Editor
Danli Xie, PhD, Wenzhou Medical University, China
Submission Status: Open until 20 March 2025
Mitochondria function in infection and immunity
Guest Editors
Rudranil De, PhD, Amity Institute of Biotechnology, Amity University Kolkata, India
Nicholas M. Maurice, MD, Emory University School of Medicine, USA
Submission Status: Open until 3 March 2025
Immune mechanisms in food allergy
Guest Editor
Katja Baerenfaller, PD, PhD, Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Switzerland
Submission Status: Open until 2 March 2025
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Aims and scope
Articles
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Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS
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Exploring the associations of plasma proteins with frailty based on Mendelian randomization
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Comparison of novel native probiotics and paraprobiotics in modulating oxidative stress and inflammation in DSS-induced colitis: implications for enhanced therapeutic strategies in high fat diet
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Role of microRNAs in immunoregulatory functions of epithelial cells
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Revisiting the white blood cell count: immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis - a prospective, observational study
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Characterization of murine macrophages from bone marrow, spleen and peritoneum
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Transcriptional profiling of the LPS induced NF-κB response in macrophages
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Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays
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HLA class I supertypes: a revised and updated classification
Editor's Choice
Convergence of endothelial dysfunction, inflammation and glucocorticoid resistance in depression-related cardiovascular diseases
Depression has been extensively linked to dysregulated HPA axis function, chronic inflammation and cardiovascular diseases. While the former two have been studied in depth, the mechanistic connection between depression and cardiovascular disease is unclear. In this review, we aim to discuss (1) endothelial dysfunction in depression, (2) inflammation in depression, (3) general glucocorticoid resistance in depression and (4) endothelial glucocorticoid resistance in depression co-morbid inflammatory diseases.
Transcriptomic evidence for atopic dermatitis as a systemic disease in NC/Nga mice
Kim and colleagues evaluated whether atopic dermatitis (AD) affects the entire body rather than being limited to skin barrier damage and inflammation. Using NC/Nga mice with AD-like symptoms, we compared the transcriptomes of the skeletal muscle (a tissue that is relatively distant from the skin) with those of the skin (the lesion induction site) before and after disease induction, after which Hc was administered. Although further study is needed to better understand the effects of Ces1d on AD, skeletal muscle was associated with AD pathogenesis, and AD-like symptoms appeared to affect the body in a systemic manner.
Annual Journal Metrics
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Citation Impact 2023
Journal Impact Factor: 2.9
5-year Journal Impact Factor: 3.3
Source Normalized Impact per Paper (SNIP): 0.775
SCImago Journal Rank (SJR): 0.815
Speed 2023
Submission to first editorial decision (median days): 14
Submission to acceptance (median days): 188
Usage 2023
Downloads: 671,800
Altmetric mentions: 176