HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.

Ahn J, Hao C, Yan J, DeLucia M, Mehrens J, Wang C, Gronenborn AM, Skowronski J
J Biol Chem. 2012 Apr 6;287(15):12550-8. doi: 10.1074/jbc.M112.340711. Epub 2012 Feb 23. (Link opens in a new window) PubMed (Link opens in a new window) Article

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